Very few people develop side-effects to TB drugs. Minor side-effects include vomiting, nausea, loss of appetite, joint pain, orange/red urine, or skin rash, which can be managed using simple medicines or adjusting the dosages of the drugs.
Major side-effects include deafness and dizziness (streptomycin); jaundice, vomiting (mainly rifampicin and isoniazid); visual impairment (ethambutol), shock, purpura, or acute renal failure (rifampicin).
These side-effects need to be managed by a trained physician and may require hospitalization.
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